All of the following are top differentials for vesicular lesions in the mouth and on the hooves of cattle except:

• A. Foot and Mouth Disease Virus
• B. Traumatic Stomatitis
• C. Malignant Catarrhal Fever Virus
• D. Vesicular Stomatitis Virus

Answer: (B)

Vesicular diseases in cattle are typically infectious conditions that produce true vesicles on mucosa and often on the hooves, so the list of top considerations includes agents like foot-and-mouth disease virus and vesicular stomatitis virus, which are classic vesicular pathogens with involvement of the oral mucosa and sometimes the coronary band. Malignant catarrhal fever virus can also cause mucosal lesions that resemble vesicles or erosions. Traumatic stomatitis, by contrast, is a non-infectious injury from mechanical irritation. It tends to produce ulcers at the site of trauma rather than true viral vesicles, and it usually doesn’t involve the hooves in the same vesicular pattern. For that reason, traumatic stomatitis is not a primary differential when you’re evaluating vesicular lesions on the mouth and hooves.