What are the most serious clinical manifestations of EHV-1 infection?

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Multiple Choice

What are the most serious clinical manifestations of EHV-1 infection?

Explanation:
EHV-1 tends to cause the most serious disease in two forms: abortion in pregnant mares and neurologic disease (myeloencephalopathy). The virus can spread from the respiratory tract into the bloodstream, leading to placental infection and fetal death, which can occur in outbreaks with substantial economic loss. It can also cause inflammation and vasculitis in the CNS, resulting in ataxia, hindlimb weakness, proprioceptive deficits, and potential recumbency; these neurologic signs can be progressive and life-threatening. Respiratory disease is common with EHV-1 but typically milder and self-limiting compared with the risk and severity of abortion or CNS involvement. Skin lesions and gastrointestinal signs are not characteristic features of EHV-1 infection, making them less relevant as the most serious manifestations. So, the most serious clinical outcomes of EHV-1 infection are abortions and neurologic signs.

EHV-1 tends to cause the most serious disease in two forms: abortion in pregnant mares and neurologic disease (myeloencephalopathy). The virus can spread from the respiratory tract into the bloodstream, leading to placental infection and fetal death, which can occur in outbreaks with substantial economic loss. It can also cause inflammation and vasculitis in the CNS, resulting in ataxia, hindlimb weakness, proprioceptive deficits, and potential recumbency; these neurologic signs can be progressive and life-threatening.

Respiratory disease is common with EHV-1 but typically milder and self-limiting compared with the risk and severity of abortion or CNS involvement. Skin lesions and gastrointestinal signs are not characteristic features of EHV-1 infection, making them less relevant as the most serious manifestations.

So, the most serious clinical outcomes of EHV-1 infection are abortions and neurologic signs.

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